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Searching relevant polymorphisms of CYP2B6 in HIV infected patients

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dc.contributor.authorTomaz, R.
dc.contributor.authorFernandes, A.
dc.contributor.authorCruz, J. P.
dc.contributor.authorMartins, R.
dc.contributor.authorMorais, J. G.
dc.contributor.authorRibeiro, A. C.
dc.date.accessioned2016-09-20T10:31:16Z
dc.date.available2016-09-20T10:31:16Z
dc.date.issued2015-11-27
dc.descriptionPoster presented at the From Basic Sciences to Clinical Research - First International Congress of CiiEM. Egas Moniz, Caparica, Portugal, 27- 28 November 2015pt_PT
dc.description.abstract"The CYP2B6 belongs to the family of Cytochrome P450 enzymes that catalyze the metabolism of a wide variety of drugs, including the anti-retroviral EFV. The CYP2B6 gene, that has been mapped in the chromosome 19, is highly polymorphic and some SNP, namely 516G>T and 785A>G, are associated with decreased protein expression. These variants are related to phenotypes that are characterized as EFV poor metabolizers, and consequently to episodes of neurotoxicity."pt_PT
dc.identifier.urihttp://hdl.handle.net/10400.26/14760
dc.language.isoengpt_PT
dc.subjectPolymorphismspt_PT
dc.subjectCYP2B6pt_PT
dc.subjectHIVpt_PT
dc.titleSearching relevant polymorphisms of CYP2B6 in HIV infected patientspt_PT
dc.typeconference object
dspace.entity.typePublication
oaire.citation.conferencePlaceEgas Moniz, Caparica, Portugalpt_PT
oaire.citation.titleFrom Basic Sciences to Clinical Research - First International Congress of CiiEMpt_PT
rcaap.rightsopenAccesspt_PT
rcaap.typeconferenceObjectpt_PT
relation.isProjectOfPublicatione22bc3ef-20a4-4173-a3c1-66d4f295e954
relation.isProjectOfPublication.latestForDiscoverye22bc3ef-20a4-4173-a3c1-66d4f295e954

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